Upright as club shortens. 

Try them STD first and look at your divots. If they are heel heavy then get them bend upright until they are flush. 

I tend to make long irons a bit more upright and wedges a bit flatter. With long irons upright you can get the ball up quicker and draw easier. . With wedges where you are hitting a lot of half shots there is less toe droop than a full swing. Toe droop flattens the effective lie angle more on a full swing  

A good test is to look where your shot pitch/ chip shots come off the face around the practice green. If they come off left , they are too upright, too flat they come off right.